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Some Things You Can Do Using the Core Facility

 

  • Quickly run very large BLAST jobs on our 44-CPU BlastMachine cluster.

  • Search for protein domains or new genes using HMMs and Genewise on the GeneMatcher2. The GeneMatcher2 hardware tremendously accelerates HMMER, Genewise, and the Smith-Waterman algorithms.

  • Look for remote homologs - run highly sensitive sequence searches using the Smith-Waterman algorithms on the GeneMatcher2 or using PSI-BLAST accelerated on the BlastMachine.

  • Develop and run parallel MPI jobs on the 90 CPU Beowulf Linux cluster, or use it as a compute farm for serial jobs.

  • Sophisticated, commercial-quality sequence and EST assembly using Paracel GenomeAssembler and Paracel Transcript Assembler.

  • We maintain the latest copies of all major sequence databases for each of our platforms - you can set up your own pipeline to run a set of queries at regular intervals against the latest data.

  • Choose from our growing list of academic software packages supported on our machines, including packages for genetic analysis and structural biology.

  • Web-based and UNIX login access to the various machines. We can host large-scale projects. We are working on technologies to allow remote use of our machines.


Scenarios for Use of the Facility.

Example Projects

 

 
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